| Calpain Inhibitor VI |
|
| Catalog Number |
9P06 |
| Three Letter Code |
4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde |
| One Letter Code |
4-Fluoro-benzenesulfonyl-VL-aldehyde |
| Synonyms |
SJA6017, 4-Fluoro-benzenesulfonyl-Val-L-leucinal |
| Molecular Formula |
C₁₇H₂₅FN₂O₄S |
| Relative Molecular Mass |
372.46 |
| CAS Registry Number |
190274-53-4 |
| Source |
Synthetic |
| Storage Conditions |
-20 ± 5 °C |
| Details |
4-Fluorobenzenesulfonyl-VL-CHO is a potent inhibitor of calpain I and II (IC₅₀ = 7.5 nM and 78 nM, respectively) but also of cathepsin B (IC₅₀ = 15 nM) and cathepsin L (IC₅₀ = 1.5 nM). The IC₅₀ values for other proteases such as interleukin 1β-converting enzyme, thrombin, factor VIIa, trypsin and chymotrypsin were above 100 µM. |
报价或需更多信息请发邮件至：alex@hanhonggroup.com，
我们一定在第一时间回复您！ |
