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GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)

H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2

  • 商品编号:151P04
  • 货  号:151P04
  • 品  牌:Hanhong
  • 缩写: HAEGTFTSDVSSYLEGQAAKEFIAWL VKGR-NH2
  • CAS: 107444-51-9
  • 英文名称: GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)
  • 分子式: C149H226N40O45
  • 分子量: 3297.68
  • 中文别名: Glucagon-Like Peptide 1 (7-36) amide (human, bovine, guinea pig, mouse, rat), Preproglucagon (98-127) amide (human, bovine, guinea pig, mouse, rat), Proglucagon (78-107) amide (human, bovine, guinea pig, mouse, rat)
  • 原价: ¥0.00
  • 现价: ¥0.00
货号 原价 现价 订购数量 库存 描述
151P04 ¥0.00 ¥0.00
0
manufacturing|Hanhong is a professional enterprise engaged in researching, developing, manufacturing and exporting unnatural amino acids ,protected amino acids and peptides. Hanhong owns advanced peptide technologies, especially in the fields of Glycopeptides, Cyclicpeptides, Methyl-peptides, Sulfication-peptides, Phosphopeptides, Active natural peptides, various Fluorescent Labled Peptides and other modification peptides, Besides, Hanhong is a fine distributor in peptide field, it has set up tide relationship with many Chinese peptide manufacturer. Based on the above advantages ,Hanhong can make custom peptide synthesis on different scale.For peptide products,Hanhong will provide detail COA, including MS,HPLC,IR spectra .^

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生物学性质Biochemistry|This GLP-1 fragment is secreted from the lower small intestine and shows a strong insulinotropic effect. GLP-1 (7-36) amide is considered as the most important incretin hormone. Its action is mediated by receptors expressed by the endocrine pancreatic B-cells. Considerable interest has focused on the development of this peptide as a therapeutic strategy for non-insulin-dependent (type 2 ) diabetes mellitus and associated neuropathy.^
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参考文献
1.Reference|G.I.Bell et al., Nature, 304, 368 (1983)B.Kreymann et al., Lancet, 2, 1300 (1987)C.Orskov and J.H.Nielsen, FEBS Lett., 229, 175 (1988)J.-P.Raufman et al., J. Biol. Chem., 267, 21432 (1992)P.A.Martin and A.Faulkner, Comp. Biochem. Biophys., 105A, 705 (1993)H.C.Fehmann et al., Peptides, 15, 453 (1994)M.A.Nauck et al., Exp. Clin. Endocrinol. Diabetes, 105, 187 (1997)T.-A.Perry and N.H.Greig, Trends Pharmacol. Sci., ^
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